SUSCEPTIBILITY OF PANCREATIC BETA CELLS TO FATTY ACIDS IS REGULATED BY LXR/PPARALPHA-DEPENDENT STEAROYL-COENZYME A DESATURASE.

Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase.

Chronically elevated levels of fatty acids-FA can cause beta cell death in vitro.Beta cells vary in their individual susceptibility to FA-toxicity.Rat beta cells were previously shown to better jilungin dreaming tea resist FA-toxicity in conditions that increased triglyceride formation or mitochondrial and peroxisomal FA-oxidation, possibly reducin

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Idiopathic pulmonary fibrosis in the era of antifibrotic therapy: Searching for new opportunities grounded in evidence

Idiopathic pulmonary fibrosis (IPF) jilungin dreaming tea is a progressive and fatal lung disease that up to now has been associated with a poor prognosis.However, the results of the INPULSIS and ASCEND trials and the approval of nintedanib and pirfenidone have marked the beginning of a new era for IPF patients.Questions remain, however.Should thes

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